Azole antifungals carry a risk of hepatotoxicity; what monitoring is recommended?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $24.99Unlock all

Prepare for the Anti-infective Medications Test with comprehensive multiple-choice questions and explanations. Dive into study materials and enhance your understanding to succeed in your exam!

Multiple Choice

Azole antifungals carry a risk of hepatotoxicity; what monitoring is recommended?

Explanation:
Azole antifungals can cause liver injury, so monitoring focuses on hepatic safety. Obtain baseline liver function tests (AST/ALT, alkaline phosphatase, bilirubin) before starting therapy, then recheck within the first one to two weeks and periodically during treatment. Increase monitoring or adjust therapy if LFTs rise significantly or if symptoms such as jaundice, right upper-quadrant pain, or fatigue appear. Other potential toxicities like kidney injury, hearing loss, or QT changes are not the primary monitoring target for this class; the emphasis here is on detecting hepatotoxicity through LFTs.

Azole antifungals can cause liver injury, so monitoring focuses on hepatic safety. Obtain baseline liver function tests (AST/ALT, alkaline phosphatase, bilirubin) before starting therapy, then recheck within the first one to two weeks and periodically during treatment. Increase monitoring or adjust therapy if LFTs rise significantly or if symptoms such as jaundice, right upper-quadrant pain, or fatigue appear. Other potential toxicities like kidney injury, hearing loss, or QT changes are not the primary monitoring target for this class; the emphasis here is on detecting hepatotoxicity through LFTs.

More Multiple Choice Questions
Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy