Vancomycin belongs to which antibiotic class?

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Prepare for the Anti-infective Medications Test with comprehensive multiple-choice questions and explanations. Dive into study materials and enhance your understanding to succeed in your exam!

Multiple Choice

Vancomycin belongs to which antibiotic class?

Explanation:
Vancomycin is a glycopeptide antibiotic. It works by binding to the D-Ala-D-Ala terminus of peptidoglycan precursors, which blocks the enzymes that cross-link the cell wall. This prevents cell wall synthesis in Gram-positive bacteria, leading to bacterial death. This mechanism is different from beta-lactams (which target PBPs and cell wall cross-linking) and from aminoglycosides (which inhibit the 30S ribosomal subunit) or macrolides (which inhibit the 50S ribosome). Glycopeptides are mainly active against Gram-positive organisms and are key for serious infections such as MRSA and, when given orally, C. difficile colitis.

Vancomycin is a glycopeptide antibiotic. It works by binding to the D-Ala-D-Ala terminus of peptidoglycan precursors, which blocks the enzymes that cross-link the cell wall. This prevents cell wall synthesis in Gram-positive bacteria, leading to bacterial death. This mechanism is different from beta-lactams (which target PBPs and cell wall cross-linking) and from aminoglycosides (which inhibit the 30S ribosomal subunit) or macrolides (which inhibit the 50S ribosome). Glycopeptides are mainly active against Gram-positive organisms and are key for serious infections such as MRSA and, when given orally, C. difficile colitis.

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